National Mesothelioma Virtual Bank

National Mesothelioma Virtual Bank
Coordinated by Department of Biomedical Informatics
University of Pittsburgh

Mesothelioma Tissue Resources Available for Your Research

Mesothelioma Virtual Bank (NMVB) (http://www.mesotissue.org/) is funded by Center for Disease Control and Prevention (CDC) in association with National Institutes of Occupational Health and Safety (NIOSH) to provide mesothelioma biospecimens with clinical annotation to researchers.

All researchers may apply for the NMVB mesothelioma tissue resources
(academic or commercial, US or foreign)

SEARCH OUR ONLINE PUBLIC DATABASE (https://www.data.nmvb.org/mvb)

Our web site features an on-line database. Investigators can search to determine whether the resource has the mesothelioma tissue samples they need for their research. Search fields include:

 

Stage of Disease Treatment Received
Histopathologic Type Recurrence Info
Histopathologic Grade Metastatic Disease
Availability of Normal Tissue Follow-up Time
Vital status, Nodal status

 

*(User must use Internet Explorer 5.5 or higher to view database)

 

Consultation and Interpretive Services:  Assistance is available from trained NMVB pathologists. The NMVB can provide consultative assistance in staining interpretation, scoring, and basic statistical analysis of NMVB TMA on a collaborative basis. These services are available from trained pathologists familiar with mesothelioma tissue microarray and immunohistochemical staining interpretation. In addition, consultation and planning for large scale studies are also available. For further details, please e-mail us at whelannb@upmc.edu .

 

Currently Available Resources:  (Further detail is available on the NMVB website)

Ø      NMVB Biospecimen Availability:
The resource has over 600 annotated cases (900 biospecimens including paraffin, fresh frozen, blood and DNA samples).

Ø      Tissue Microarray (TMA):
The NMVB is now pleased to announce the availability of slides from mesothelioma TMA with associated clinical data.

Currently Available TMA Constructed Based On: Samples from 40 patients have been incorporated: 36 patients have tissue cores from the primary lesion only, 3 patients have tissue cores from a metastatic lesion only, and 1 patient has tissue cores from both the primary and metastatic lesions. Of the patients with available clinical annotation, 97% are male and 3% are female, and racial breakdown is as follows: 57% white, 3% black, and 39% unknown.

The information provided for each case on the array includes over 25 data elements including: age at diagnosis, race, asbestoses exposure, tumor size, histologic type, TNM staging, grade, and vital status.


 

An application form for paraffin or frozen tissues and TMA is available at [http://www.mesotissue.org/apply.htm].
Please e-mail us at whelannb@upmc.edu if you have any questions about our TMA or our large repository of paraffin-embedded and fresh-frozen mesothelioma tissue samples.  

 

 


 

 

 

 


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Contact us here for immediate expert help and a free copy of the book "100 Questions & Answers About Mesothelioma."

(877) END-MESO
(877) 363-6376