Letter from the President and CEO

Dear CureSearch Supporters,

As I write to you about the important research CureSearch funds to find a cure for all children with cancer, I am troubled by a newly released report from the National Institutes of Health (NIH) about cancer in the United States.

In the report, the NIH announced that while the survival rate for children's cancer has steadily increased in recent years, the number of children being diagnosed has continued to increase, too. As we search for a cure, we must also understand why the number of children with cancer is on the rise and what can be done to reverse this trend. Read the full letter

Ultimate Hike is Coming to a Location near You

If you crave adventure, love the outdoors and welcome a challenge, then this is the experience for you! Ultimate Hike is a day-long, challenging hike of 15-35 miles that takes place in a spectacular natural setting. Through Ultimate Hike, you will challenge yourself, meet new people and join the fight to cure children's cancer. Read more

Scientists Discover Cell that Causes Rhabdomyosarcoma

Knowing the genetic and cellular origins of cancer helps clinicians design specific
therapies that work best for each individual cancer.

In a study funded by the Scott Carter Foundation at a CureSearch for Children's Cancer-affiliated laboratory, researchers at Oregon Health & Science University, Doernbecher Children's Hospital have defined the cell-of-origin for rhabdomyosarcoma, or muscle cancer. In a study published in the journal Cancer Cell, the authors report that childhood and adult sarcomas are linked in their biology, mutations, and cells from which these tumors first start. These findings may lead to non-chemotherapy medicines that can inhibit "molecular targets" such as growth factor receptors, which would stop or eliminate the disease. Read more

Spotlight on Jack Rolle

In 2008, 10-year old Jack Rolle was a healthy boy with a zest for life. He enjoyed sports -- especially golf -- as well as school and playing with his three brothers. That summer, Jack became excessively thirsty and was going to the bathroom more than normal. Naturally concerned, Jack's parents took him to the doctor and discovered after some tests that he had diabetes insipidus, a disease characterized by the body's inability to regulate fluids. While Jack responded well to medication for diabetes insipidus, his doctors ordered an MRI to determine the underlying cause of the disease. Read more

CureSearch for Children's Cancer and Flashes of Hope Team Up to Take Kick-It Nationwide

Kick-It was created by Quinn Clarke when he was 10 years old and facing yet another round of cancer treatment. Quinn's dream was to cure cancer by playing his favorite game - kickball. On just 5 days notice, more than 500 people came together and raised thousands of dollars. Within weeks, games were held in backyards, parks and playgrounds all over the country proving that everyone - kids, adults, friends and families - can make a difference in the lives of children with cancer. Read more

Spotlight on Charles Keller, MD

Charles Keller, MD, knew he wanted to be a physician-scientist but trained as biomedical engineer. He never dreamed he would end up a specialist in developing more effective and less toxic medications for rhabdomyosarcoma and medulloblastoma. However, as a young medical student, he was struck by the courage of children and adolescents in the oncology unit. Read more

Children's Cancer Research Network

CureSearch for Children's Cancer is pleased to announce that nearly 200 Children's Oncology Group hospitals received payments for enrolling patients in the Children's Cancer Research Network over the last nine months. These payments total over $750,000 and were made possible by CureSearch philanthropic donors. CCRN is a repository of data and a tool that allows statisticians to follow patients into adulthood. Read more

Young Investigator Funding

Congratulations to this year's recipients of the CureSearch Research Fellowship Awards:

• Pooja Hingorani, MD, Phoenix Children's Hospital
• J. Kimble Frazer, MD, University of Utah
• Jeffrey Knipstein,MD, University of Colorado

Read more

The CureSearch Walk celebrates and honors all those whose lives have been affected by children's cancer, while raising much-needed funds for children's cancer research. Last year, more than 14,000 people participated in The CureSearch Walk, and this year we hope to break the 20,000 participant mark.

You can help by recruiting your family, friends, co-workers, neighbors and other members of your community to raise funds for children's cancer research at one of our 50 CureSearch Walk events nationwide.

Together, we can conquer children's cancer.
Visit curesearchwalk.org.

Aflac Foundation Funds Young Investigators in Adolescent and Young Adult Oncology

The Aflac Foundation has once again provided critically-needed support for young investigators pursuing an academic career with an emphasis on adolescents and young adults (AYA) with cancer. This area is of particular interest to the Children's Oncology Group, which is the first-and to date only-cooperative clinical trials organization in North America to have an AYA Committee dedicated to conducting research in this age group. Read more

Children's Cancer Awareness and Advocacy Day

While more than 170 visits were made to House and Senate offices from 28 states, CureSearch recently learned that there will be a reduction in this year's federal funding to the Children's Oncology Group of nearly 10 percent. CureSearch will continue to ask Congress to support children's cancer research and to participate in the annual Congressional Pediatric Cancer Caucus event
in September. Read more

CureSearch Names New Board Leadership

In January 2011, CureSearch for Children's Cancer named Stuart Siegel, MD, chair of the Board of Directors and Deborah Pryce vice chair of the Board of Directors. Both Siegel and Pryce have been members of the CureSearch Board for a number of years and instrumental in advancing the organization's mission. Read more

Peter C. Adamson, MD, Assumes Top Leadership Position for the COG

On January 1, 2011, Peter C. Adamson, MD, assumed the role of Chair of the Children's Oncology Group (COG). Dr. Adamson is also Chief of the Division of Clinical Pharmacology & Therapeutics at Children's Hospital of Philadelphia, having served as its Director for Clinical & Translational Research through 2009. Read more

New Listserv for Parents of Infants with ALL

Visit a new online community for parents and caregivers of infants with ALL to discuss the many aspects of care and treatment, including the emotional, social and financial challenges. The listserv is a way to connect with others who know what it feels like to experience the same issues and challenges you may be facing. Founded by families for families, this new listserv is part of the Association of Cancer Online Resources. To join, visit their website.

CureSearch for Children's Cancer Regional Offices

Western Region
Kelley Driscoll
Regional Development Manager
440 E. Huntington Drive
Suite 400
Arcadia, CA 91006
Phone: (626) 241-1637
westcoast@curesearch.org

Southeast Region
Amy E. Brindley
Regional Development Director
National Corporate Relations Director
200 South Tryon Street
Suite 1200
Charlotte, NC 28202
Phone: (704) 285-6513
southeast@curesearch.org

Midwest Region
Megan Selck
Regional Development Director Midwest Region
300 South Carlton Ave.
Suite 150
Wheaton, IL 60187
Phone: (331) 223-5313
midwest@curesearch.org

Northeast Region
Azalea M. Candelaria
Regional Development Director
National Director of Corporate Relations
4600 East West Highway
Suite 600
Bethesda, MD 20814
Direct: (240) 235-2240
northeast@curesearch.org

Southwest Region
Julia Juo
Regional Development Director
14850 Quorum Drive
Suite 145
Dallas, Texas 75254
Phone: (214) 843-5256
southwest@curesearch.org